MGA Rabbit Polyclonal Antibody

CAT#: TA356660

MGA Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: MGA Sample Type: 721_B Whole Cell lysates Antibody Dilution: 1.0ug/mlMGA is supported by BioGPS gene expression data to be expressed in 721_B

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human MGA
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 92%; Dog: 85%; Horse: 92%; Human: 100%; Mouse: 79%; Pig: 92%; Rabbit: 79%; Rat: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 76kDa
• Gene Name: MGA, MAX dimerization protein
• Database Link:
  Entrez Gene 23269 Human
  UniProt ID Q8IWI9-2
• Background: MGA functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes and functions as a repressor or an activator. It binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. It suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. It function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor
• Synonyms: FLJ12634; KIAA0518; MAD5; MGAM; MXD5