MDFI Rabbit Polyclonal Antibody

CAT#: TA356874

MDFI Antibody - middle region

Product Images

Host: Rabbit Target Name: MDFI Sample Type: RPMI-8226 Whole Cell lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human MDFI
• Specificity: Expected reactivity: Cow, Dog, Human, Pig, Rabbit, Sheep
  Homology: Cow: 79%; Dog: 79%; Human: 100%; Pig: 86%; Rabbit: 79%; Sheep: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 27kDa
• Gene Name: MyoD family inhibitor
• Database Link:
  NP_005577
  Entrez Gene 4188 Human
  UniProt ID Q99750
• Background: This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
• Synonyms: I-MF; I-mfa; OTTHUMP00000196414