IL7 Rabbit Polyclonal Antibody

CAT#: TA357161

IL7 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: IL7 Sample Type: 721_B Whole Cell lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human IL7
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Pig, Sheep, Yeast
  Homology: Cow: 86%; Dog: 86%; Horse: 93%; Human: 100%; Pig: 100%; Sheep: 93%; Yeast: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 19kDa
• Gene Name: interleukin 7
• Database Link:
  Entrez Gene 3574 Human
  UniProt ID P13232
• Background: The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.
• Synonyms: IL-7