GRB2 Rabbit Polyclonal Antibody

CAT#: TA357448

GRB2 Antibody - N-terminal region

Product Images

GRB2 antibody - N-terminal region (TA357448) validated by WB using 721_B cell Lysate at 1ug/ml.GRB2 is supported by BioGPS gene expression data to be expressed in 721_B

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  GRB2 antibody - N-terminal region (TA357448) validated by WB using 1. and 2. Human Cystic Fibrosis Bronchial Epithelial Cells (35ug) Primary Dilution: 1:500Secondary Anitbody: goat anti-rabbit-HRPSecondary Dilution: 1:5000Image Submitted By: Dr. Haouaria BalghiMcGill University

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  Sample Type:Â 2. mouse brain extracts (80ug) Primary Antibody Dilution:Â 2ug/ml Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience Secondary Antibody Dilution:Â 1: 20,000 Image Submitted by: Yuzhi Chen University of Arkansas for Medical ScienceÂ

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  Host: Mouse Target Name: GRB2 Sample Tissue: Mouse Kidney Antibody Dilution: 1ug/ml

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  Rabbit Anti-GRB2 Antibody Catalog Number: TA357448 Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue Observed Staining: Cytoplasm Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec

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Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 24kDa
• Gene Name: growth factor receptor bound protein 2
• Database Link:
  NP_002077
  Entrez Gene 14784 MouseEntrez Gene 2885 Human
  UniProt ID P62993
• Background: The protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: AA408164; Ash; MGC108668

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Acute myeloid leukemia, B cell receptor signaling pathway, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Dorso-ventral axis formation, Endometrial cancer, ErbB signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, Gap junction, Glioma, GnRH signaling pathway, Insulin signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pathways in cancer, Prostate cancer, Renal cell carcinoma, T cell receptor signaling pathway