AXL Rabbit Polyclonal Antibody

CAT#: TA357509

AXL Antibody - C-terminal region

Product Images

WB Suggested Anti-AXL Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: Human Placenta

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human AXL
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rat
  Homology: Cow: 79%; Dog: 79%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 85%; Pig: 86%; Rat: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 97kDa
• Gene Name: AXL receptor tyrosine kinase
• Database Link:
  NP_001690
  Entrez Gene 558 Human
  UniProt ID P30530
• Background: The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified.
• Synonyms: JTK11; UFO

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Transmembrane