PAR2 (F2RL1) Rabbit Polyclonal Antibody

CAT#: TA357656

F2RL1 Antibody - C-terminal region

Product Images

WB Suggested Anti-F2RL1 Antibody Titration: 1.0 ug/ml Positive Control: MCF7 Whole Cell

• 

  Host: Rabbit Target Name: F2RL1 Sample Tissue: Human Jurkat Whole Cell Antibody Dilution: 0.5ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Dog, Guinea Pig, Human, Rat
  Homology: Dog: 93%; Guinea Pig: 86%; Human: 100%; Rat: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 44kDa
• Gene Name: F2R like trypsin receptor 1
• Database Link:
  NP_005233
  Entrez Gene 2150 Human
  UniProt ID P55085
• Background: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83% identical to the mouse receptor sequence.
• Synonyms: GPR11; PAR-2; PAR2

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction