Prom1 Rabbit Polyclonal Antibody

CAT#: TA357801

Prom1 Antibody - N-terminal region

Product Images

WB Suggested Anti-Prom1 Antibody Titration: 1.0 ug/ml Positive Control: Mouse Liver

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  Host: Rabbit Target Name: Prom1 Sample Type: Mouse Liver Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1ug/ml Peptide Concentration: 5ug/ml Lysate Quantity: 25ug/lane/Lane Gel Concentration: 0.12

Specifications

Product Data

• Applications: WB
• Reactivities: Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat, Zebrafish
  Homology: Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 92%; Human: 100%; Mouse: 85%; Rat: 91%; Zebrafish: 92%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 95kDa
• Gene Name: prominin 1
• Database Link:
  NP_001157049
  Entrez Gene 19126 Mouse
  UniProt ID O54990
• Background: Prom1 binds cholesterol in cholesterol-containing plasma membrane microdomains. It is rroposed to play a role in apical plasma membrane organization of epithelial cells. During early during retinal development, Prom1 acts as a key regulator of disk morphogenesis. Prom1 is involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.
• Synonyms: AC133; CD133; CORD12; hProminin; MCDR2; MSTP061; PROML1; RP41; STGD4