CysLT1 (CYSLTR1) Rabbit Polyclonal Antibody

CAT#: TA357849

CYSLTR1 Antibody - C-terminal region

Product Images

WB Suggested Anti-CYSLTR1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Rabbit
  Homology: Cow: 93%; Dog: 86%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Rabbit: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 37kDa
• Gene Name: cysteinyl leukotriene receptor 1
• Database Link:
  NP_006630
  Entrez Gene 10800 Human
  UniProt ID Q9Y271
• Background: The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
• Synonyms: CysLT(1); CYSLT1; CYSLT1R; CYSLTR; HG55; HMTMF81; MGC46139

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction