LGI1 Rabbit Polyclonal Antibody

CAT#: TA357885

LGI1 Antibody - N-terminal region

Product Images

WB Suggested Anti-LGI1 Antibody Titration: 1.0 ug/ml Positive Control: HCT15 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 61kDa
• Gene Name: leucine-rich, glioma inactivated 1
• Database Link:
  NP_005088
  Entrez Gene 9211 Human
  UniProt ID O95970
• Background: This gene is rearranged as a result of translocations in glioblastoma cell lines. The protein contains a hydrophobic segment representing a putative transmembrane domain with the amino terminus located outside the cell. It also contains leucine-rich repeats with conserved cysteine-rich flanking sequences. This gene is predominantly expressed in neural tissues and its expression is reduced in low grade brain tumors and significantly reduced or absent in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy.
• Synonyms: EPITEMPIN; Epitempin-1; EPT; ETL1; IB1099

Reference Data

• Protein Families: Druggable Genome, Secreted Protein