TNIP1 Rabbit Polyclonal Antibody
Other products for "TNIP1"
Specifications
Product Data | |
Applications | WB |
Reactivities | Human |
Host | Rabbit |
Clonality | Polyclonal |
Specificity | Expected reactivity: Dog, Horse, Human Homology: Dog: 92%; Horse: 86%; Human: 100% |
Formulation | Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage | For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Predicted Protein Size | 70kDa |
Gene Name | TNFAIP3 interacting protein 1 |
Database Link | |
Background | TNIP1 interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP- or TRAF2-mediated transactivation signal. TNIP1 increases cell surface CD4(T4) antigen expression. TNIP1 interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. TNIP1 may regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production. |
Synonyms | ABIN-1; hVAN; KIAA0113; NAF1; Nip40-1; VAN |
Reference Data |
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