VAC14 Rabbit Polyclonal Antibody

CAT#: TA357939

VAC14 Antibody - C-terminal region

Product Images

WB Suggested Anti-VAC14 Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 77%; Horse: 93%; Human: 100%; Mouse: 92%; Pig: 79%; Rabbit: 79%; Rat: 92%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 86kDa
• Gene Name: Vac14, PIKFYVE complex component
• Database Link:
  NP_060522
  Entrez Gene 55697 Human
  UniProt ID Q08AM6
• Background: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE and the PtdIns(3,5)P2 phosphatase FIG4. VAC14 functions as an activator of PIKFYVE.
• Synonyms: ArPIKfyve; FLJ10305; FLJ36622; FLJ46582; MGC149815; MGC149816; TAX1BP2; TRX