PFKFB1 Rabbit Polyclonal Antibody

CAT#: TA357983

PFKFB1 Antibody - C-terminal region

Product Images

WB Suggested Anti-PFKFB1 Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 100%; Zebrafish: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 52kDa
• Gene Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
• Database Link:
  NP_002616
  Entrez Gene 5207 Human
  UniProt ID Q4VBA8
• Background: This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis.
• Synonyms: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatas; F6PK; fructose-6-phosphate,2-kinase:fructose-2,6-bisphos; HL2K; MGC116715; MGC116717; PFRX

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Fructose and mannose metabolism