DUSP9 Rabbit Polyclonal Antibody

CAT#: TA358028

DUSP9 Antibody - middle region

Product Images

WB Suggested Anti-DUSP9 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast
  Homology: Cow: 79%; Dog: 93%; Guinea Pig: 85%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 92%; Rat: 100%; Yeast: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 42kDa
• Gene Name: dual specificity phosphatase 9
• Database Link:
  NP_001386
  Entrez Gene 1852 Human
  UniProt ID Q99956
• Background: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases, is expressed only in placenta, kidney, and fetal liver, and is localized to the cytoplasm and nucleus.
• Synonyms: MKP-4; MKP4; OTTHUMP00000025953

Reference Data

• Protein Families: Phosphatase
• Protein Pathways: MAPK signaling pathway