Cul4b Rabbit Polyclonal Antibody

CAT#: TA358045

Cul4b Antibody - C-terminal region

Product Images

WB Suggested Anti-Cul4b Antibody Titration: 1.0 ug/ml Positive Control: Mouse Heart

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  WB Suggested Anti-Cul4b Antibody Positive Control: Lane 1: 50ug 293T lysate Lane 2: 50ug hCUL4B transfected 293T lysate Primary Antibody Dilution : 1:1000 Secondary Antibody : Anti-rabbit-HRP Secondry Antibody Dilution : 1:10,000 Submitted by: Mei Yang

Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Goat: 86%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 111kDa
• Gene Name: cullin 4B
• Database Link:
  NP_001103612
  Entrez Gene 8450 HumanEntrez Gene 72584 Mouse
  UniProt ID A2A432
• Background: Cul4b is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition subunit. CUL4B may act within the complex as a scaffold protein, contributing to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme.
• Synonyms: CUL-4B; cullin-4B; DKFZp686F1470; KIAA0695; MRXHF2; MRXSC; SFM2