CHMP2A Rabbit Polyclonal Antibody

CAT#: TA358066

CHMP2A Antibody - N-terminal region

Product Images

WB Suggested Anti-CHMP2A Antibody Titration: 1.0 ug/ml Positive Control: Fetal Lung

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Goat, Guinea Pig, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Goat: 90%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 24kDa
• Gene Name: charged multivesicular body protein 2A
• Database Link:
  NP_055268
  Entrez Gene 27243 Human
  UniProt ID O43633
• Background: CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression.
• Synonyms: BC-2; BC2; CHMP2; hVps2-1; VPS2; Vps2-1; VPS2A

Reference Data

• Protein Pathways: Endocytosis