HSD17B8 Rabbit Polyclonal Antibody

CAT#: TA358076

HSD17B8 Antibody - N-terminal region

Product Images

WB Suggested Anti-HSD17B8 Antibody Titration: 1.0 ug/ml Positive Control: RPMI-8226 Whole CellHSD17B8 is supported by BioGPS gene expression data to be expressed in RPMI 8226

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 29kDa
• Gene Name: hydroxysteroid (17-beta) dehydrogenase 8
• Database Link:
  NP_055049
  Entrez Gene 7923 Human
  UniProt ID Q92506
• Background: In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.
• Synonyms: D6S2245E; dJ1033B10.9; FABG; FABGL; H2-KE6; HKE6; Ke-6; KE6; RING2; SDR30C1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Androgen and estrogen metabolism, Metabolic pathways