MTMR6 Rabbit Polyclonal Antibody

CAT#: TA358095

MTMR6 Antibody - C-terminal region

Product Images

WB Suggested Anti-MTMR6 Antibody Titration: 1.0 ug/ml Positive Control: NCI-H226 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Dog, Guinea Pig, Horse, Human, Rabbit, Rat
  Homology: Dog: 93%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Rabbit: 86%; Rat: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 68kDa
• Gene Name: myotubularin related protein 6
• Database Link:
  NP_004676
  Entrez Gene 9107 Human
  UniProt ID Q9Y217
• Background: MTMR6 phosphatase that acts on lipids with a phosphoinositol headgroup. It acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol-3 phosphatase. It negatively regulates proliferation of reactivated CD4+ T-cells.
• Synonyms: MTMR6

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism