Eif3d Rabbit Polyclonal Antibody

CAT#: TA358161

Eif3d Antibody - N-terminal region

Product Images

WB Suggested Anti-Eif3d Antibody Titration: 1.0 ug/ml Positive Control: Rat liver

Specifications

Product Data

• Applications: WB
• Reactivities: Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Yeast, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 60kDa
• Gene Name: eukaryotic translation initiation factor 3, subunit D
• Database Link:
  NP_001004283
  Entrez Gene 362952 Rat
  UniProt ID Q6AYK8
• Background: Eif3d is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
• Synonyms: eIF-3-zeta; eIF3-p66; eIF3-zeta; EIF3S7; MGC17258; MGC126526; OTTHUMP00000197901