MRPL40 Rabbit Polyclonal Antibody

CAT#: TA358187

MRPL40 Antibody - middle region

Product Images

WB Suggested Anti-MRPL40 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Liver

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Guinea Pig: 77%; Horse: 79%; Human: 100%; Mouse: 75%; Rabbit: 77%; Rat: 83%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 23kDa
• Gene Name: mitochondrial ribosomal protein L40
• Database Link:
  NP_002937
  Entrez Gene 6118 HumanEntrez Gene 64976 Human
  UniProt ID P15927
• Background: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Deletions in this gene may contribute to the etiology of velo-cardio-facial syndrome and DiGeorge syndrome.
• Synonyms: FLJ41774; L40mt; MGC9400; MRP-L22; MRP-L40; NLVCF; URIM

Reference Data

• Protein Families: Druggable Genome, Stem cell - Pluripotency
• Protein Pathways: DNA replication, Homologous recombination, Mismatch repair, Nucleotide excision repair