Acrosin (ACR) Rabbit Polyclonal Antibody

CAT#: TA358324

ACR Antibody - C-terminal region

Product Images

WB Suggested Anti-ACR Antibody Titration: 1.0 ug/ml Positive Control: Fetal Lung

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Horse, Human, Sheep
  Homology: Cow: 79%; Horse: 79%; Human: 100%; Sheep: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 46kDa
• Gene Name: acrosin
• Database Link:
  NP_001088
  Entrez Gene 49 Human
  UniProt ID P10323
• Background: Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.
• Synonyms: acrosin; ACRS; preproacrosin; proacrosin

Reference Data

• Protein Families: Druggable Genome, Protease