Poliovirus Receptor (PVR) Rabbit Polyclonal Antibody

CAT#: TA358325

PVR Antibody - N-terminal region

Product Images

WB Suggested Anti-PVR Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell

• 

  Host: Rabbit Target: PVR Positive control (+): Hela (HL) Negative control (-): Human brain (BR) Antibody concentration: 1ug/ml

• 

  Researcher: Dr. Fabio D'Amico, University of Catania Application: IHC Species+tissue/cell type:Human Keratinocytes Primary antibody dilution: 1:200 Secondary antibody: Anti-rabbit Dylight 488 Secondary antibody dilution:1:500

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 45kDa
• Gene Name: poliovirus receptor
• Database Link:
  NP_006496
  Entrez Gene 5817 Human
  UniProt ID P15151
• Background: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.
• Synonyms: CD155; FLJ25946; HVED; Necl-5; NECL5; PVS; Tage4

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)