OSCAR Rabbit Polyclonal Antibody

CAT#: TA358338

OSCAR Antibody - C-terminal region

Product Images

WB Suggested Anti-OSCAR Antibody Titration: 1.0 ug/ml Positive Control: Fetal Kidney

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 29kDa
• Gene Name: osteoclast associated, immunoglobulin-like receptor
• Database Link:
  NP_570127
  Entrez Gene 126014 Human
  UniProt ID Q8IYS5-3
• Background: Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: hOSCAR; MGC33613; PIGR3

Reference Data

• Protein Families: Druggable Genome