NF2 Rabbit Polyclonal Antibody

CAT#: TA358369

NF2 Antibody - C-terminal region

Product Images

WB Suggested Anti-NF2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Brain

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  Host: Rabbit Target Name: NF2 Sample Type: Human Fetal Kidney Antibody Dilution: 1.0ug/ml

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  Host: Rabbit Target Name: NF2 Sample Type: Human 293T Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 56kDa
• Gene Name: neurofibromin 2 (merlin)
• Database Link:
  NP_861968
  Entrez Gene 4771 Human
  UniProt ID P35240-4
• Background: This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts.
• Synonyms: ACN; BANF; merlin; Neurofibromin-2; SCH; schwannomerlin; Schwannomin

Reference Data

• Protein Families: Druggable Genome