SDHC Rabbit Polyclonal Antibody

CAT#: TA358435

SDHC Antibody - middle region

Product Images

WB Suggested Anti-SDHC Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell

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  Host: Rabbit Target: SDHC Positive control (+): HepG2 Cell Lysate (HG) Negative control (-): HeLa Cell Lysate (HL) Antibody concentration: 5ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human
  Homology: Human: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 17kDa
• Gene Name: succinate dehydrogenase complex subunit C
• Database Link:
  NP_001030588
  Entrez Gene 6391 Human
  UniProt ID Q99643-2
• Background: This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.
• Synonyms: CYB560; CYBL; PGL3; QPs-1; QPs1; SDH3

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Alzheimer's disease, Citrate cycle (TCA cycle), Huntington's disease, Metabolic pathways, Oxidative phosphorylation, Parkinson's disease