HTRA1 Rabbit Polyclonal Antibody

CAT#: TA358468

HTRA1 Antibody - N-terminal region

Product Images

WB Suggested Anti-HTRA1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Kidney

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  Rabbit Anti-HTRA1 Antibody Catalog Number: TA358468 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Cytoplasmic Primary Antibody Concentration: 1:100 Other Working Concentrations: 1:600 Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec

Specifications

Product Data

• Applications: IHC, WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Human, Mouse, Pig, Rat
  Homology: Cow: 100%; Human: 100%; Mouse: 92%; Pig: 100%; Rat: 92%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 53kDa
• Gene Name: HtrA serine peptidase 1
• Database Link:
  NP_002766
  Entrez Gene 5654 Human
  UniProt ID Q92743
• Background: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.
• Synonyms: ARMD7; HTRA; IGFBP5-protease; L56; ORF480; PRSS11

Reference Data

• Protein Families: Druggable Genome, Protease, Secreted Protein