MC2 receptor (MC2R) Rabbit Polyclonal Antibody

CAT#: TA358503

MC2R Antibody - N-terminal region

Product Images

WB Suggested Anti-MC2R Antibody Titration: 1.0 ug/ml Positive Control: Fetal kidney

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Sheep
  Homology: Cow: 79%; Dog: 93%; Guinea Pig: 85%; Horse: 86%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%; Sheep: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 33kDa
• Gene Name: melanocortin 2 receptor
• Database Link:
  NP_000520
  Entrez Gene 4158 Human
  UniProt ID Q01718
• Background: MC2R encodes one member of the five-member G-protein associated melanocortin receptor family. Melanocortins (melanocyte-stimulating hormones and adrenocorticotropic hormone) are peptides derived from pro-opiomelanocortin (POMC). MC2R is selectively activated by adrenocorticotropic hormone, whereas the other four melanocortin receptors recognize a variety of melanocortin ligands. Mutations in MC2R can result in familial glucocorticoid deficiency.
• Synonyms: ACTH-R; ACTHR; MC2-R; MGC125798; OTTHUMP00000162512

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction