IL1 Receptor I (IL1R1) Rabbit Polyclonal Antibody

CAT#: TA358567

IL1R1 Antibody - C-terminal region

Product Images

WB Suggested Anti-IL1R1 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart

• 

  WB Suggested Anti-IL1R1 Antibody Positive Control: Lane 1: 60ug human NT2 cell line Primary Antibody Dilution : 1:500 Secondary Antibody : IRDye 800 CW goat anti-rabbit from Li-COR Bioscience Secondry Antibody Dilution : 1:20,000 Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 92%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 63kDa
• Gene Name: interleukin 1 receptor type 1
• Database Link:
  NP_000868
  Entrez Gene 3554 Human
  UniProt ID P14778
• Background: The protein encoded by this gene is a cytokine receptor that belongs to the interleukin 1 receptor family. This protein is a receptor for interleukin alpha (IL1A), interleukin beta (IL1B), and interleukin 1 receptor, type I(IL1R1/IL1RA). It is an important mediator involved in many cytokine induced immune and inflammatory responses. This gene along with interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 2 (IL1RL2), and interleukin 1 receptor-like 1 (IL1RL1) form a cytokine receptor gene cluster in a region mapped to chromosome 2q12.
• Synonyms: CD121A; D2S1473; IL-1R-1; IL-1R-alpha; IL-1RT1; IL1R; IL1RA; IL1RT1; OTTHUMP00000161344; P80

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Apoptosis, Cytokine-cytokine receptor interaction, Hematopoietic cell lineage, MAPK signaling pathway