PPP1R14A Rabbit Polyclonal Antibody

CAT#: TA358580

PPP1R14A Antibody - N-terminal region

Product Images

WB Suggested Anti-PPP1R14A Antibody Titration: 1.0 ug/ml Positive Control: PANC1 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Human, Mouse, Pig, Rabbit, Rat
  Homology: Cow: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 17kDa
• Gene Name: protein phosphatase 1 regulatory inhibitor subunit 14A
• Database Link:
  NP_150281
  Entrez Gene 94274 Human
  UniProt ID Q96A00
• Background: The protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
• Synonyms: CPI-17; CPI17; PPP1INL

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Vascular smooth muscle contraction