SHANK2 Rabbit Polyclonal Antibody

CAT#: TA358608

SHANK2 Antibody - C-terminal region

Product Images

WB Suggested Anti-SHANK2 Antibody Titration: 1.0 ug/ml Positive Control: Jurkat Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rat
  Homology: Cow: 100%; Dog: 85%; Guinea Pig: 77%; Horse: 100%; Human: 100%; Mouse: 85%; Rat: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 135kDa
• Gene Name: SH3 and multiple ankyrin repeat domains 2
• Database Link:
  NP_036441
  Entrez Gene 22941 Human
  UniProt ID Q9UPX8-4
• Background: This gene encodes a protein that is a member of the Shank family of synaptic proteins that may function as molecular scaffolds in the postsynaptic density (PSD). Shank proteins contain multiple domains for protein-protein interaction, including ankyrin repeats, an SH3 domain, a PSD-95/Dlg/ZO-1 domain, a sterile alpha motif domain, and a proline-rich region. This particular family member contains a PDZ domain, a consensus sequence for cortactin SH3 domain-binding peptides and a sterile alpha motif. The alternative splicing demonstrated in Shank genes has been suggested as a mechanism for regulating the molecular structure of Shank and the spectrum of Shank-interacting proteins in the PSDs of adult and developing brain.
• Synonyms: CORTBP1; CTTNBP1; KIAA1022; ProSAP1; SHANK; SPANK-3