IL19 Rabbit Polyclonal Antibody

CAT#: TA358617

IL19 Antibody - middle region

Product Images

WB Suggested Anti-IL19 Antibody Titration: 1 ug/ml Positive Control: Placenta

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Human, Rabbit, Rat
  Homology: Cow: 79%; Dog: 86%; Human: 100%; Rabbit: 79%; Rat: 79%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 18kDa
• Gene Name: interleukin 19
• Database Link:
  NP_715639
  Entrez Gene 29949 Human
  UniProt ID Q5VUT3
• Background: The protein encoded by this gene is a cytokine that belongs to the IL10 cytokine subfamily. This cytokine is found to be preferentially expressed in monocytes. It can bind the IL20 receptor complex and lead to the activation of the signal transducer and activator of transcription 3 (STAT3). A similar cytokine in mouse is reported to up-regulate the expression of IL6 and TNF-alpha and induce apoptosis, which suggests a role of this cytokine in inflammatory responses. Alternatively spliced transcript variants encoding the distinct isoforms have been described.
• Synonyms: IL-10C; IL-19; MDA1; NG.1; ZMDA1

Reference Data

• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway