GPBAR1 Rabbit Polyclonal Antibody

CAT#: TA358645

GPBAR1 Antibody - C-terminal region

Product Images

WB Suggested Anti-GPBAR1 Antibody Titration: 1.0 ug/ml Positive Control: MCF7 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Human, Rat
  Homology: Human: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 35kDa
• Gene Name: G protein-coupled bile acid receptor 1
• Database Link:
  NP_733800
  Entrez Gene 151306 Human
  UniProt ID Q8TDU6
• Background: This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
• Synonyms: BG37; GPCR; GPCR19; GPR131; hBG37; hGPCR19; M-BAR; MGC40597; TGR5

Reference Data

• Protein Families: Druggable Genome