NEIL2 Rabbit Polyclonal Antibody

CAT#: TA358675

NEIL2 Antibody - N-terminal region

Product Images

WB Suggested Anti-NEIL2 Antibody Titration: 1.0 ug/ml Positive Control: THP-1 Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rabbit: 100%; Rat: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 30kDa
• Gene Name: nei like DNA glycosylase 2
• Database Link:
  NP_001129219
  Entrez Gene 252969 Human
  UniProt ID Q969S2-3
• Background: NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction.
• Synonyms: FLJ31644; MGC2832; MGC4505; NEH2; NEI2

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair