CDC14A Rabbit Polyclonal Antibody

CAT#: TA358687

CDC14A Antibody - C-terminal region

Product Images

WB Suggested Anti-CDC14A Antibody Titration: 1.0 ug/ml Positive Control: RPMI-8226 Whole CellCDC14A is strongly supported by BioGPS gene expression data to be expressed in Human RPMI-8226 cells

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat
  Homology: Cow: 100%; Dog: 87%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 66kDa
• Gene Name: cell division cycle 14A
• Database Link:
  NP_003663
  Entrez Gene 8556 Human
  UniProt ID Q9UNH5
• Background: The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.
• Synonyms: cdc14; Cdc14A1; Cdc14A2; hCDC14

Reference Data

• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Cell cycle