PIG3 (TP53I3) Rabbit Polyclonal Antibody

CAT#: TA358729

TP53I3 Antibody - C-terminal region

Product Images

WB Suggested Anti-TP53I3 Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole CellTP53I3 is supported by BioGPS gene expression data to be expressed in HepG2

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Horse, Human, Pig, Rabbit
  Homology: Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 86%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 35kDa
• Gene Name: tumor protein p53 inducible protein 3
• Database Link:
  NP_004872
  Entrez Gene 9540 Human
  UniProt ID Q53FA7
• Background: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.
• Synonyms: PIG3

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: p53 signaling pathway