SUCLA2 Rabbit Polyclonal Antibody

CAT#: TA358760

SUCLA2 Antibody - N-terminal region

Product Images

WB Suggested Anti-SUCLA2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Heart

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Yeast, Zebrafish
  Homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 45kDa
• Gene Name: succinate-CoA ligase ADP-forming beta subunit
• Database Link:
  NP_003841
  Entrez Gene 8803 Human
  UniProt ID Q9P2R7
• Background: Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
• Synonyms: A-BETA; SCS-betaA

Reference Data

• Protein Pathways: Citrate cycle (TCA cycle), Metabolic pathways, Propanoate metabolism