Hemoglobin subunit gamma 2 (HBG2) Rabbit Polyclonal Antibody

CAT#: TA358774

HBG2 Antibody - middle region

Product Images

WB Suggested Anti-HBG2 Antibody Titration: 1.0 ug/ml Positive Control: Fetal Kidney

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  Host: Rabbit Target Name: FAM46C Sample Type: Human Fetal Liver Antibody Dilution: 1.0ug/ml

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  Host: Rabbit Target Name: NSUN6 Sample Type: Human Fetal Lung Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Goat, Guinea Pig, Horse, Human, Mouse, Pig, Rabbit, Rat, Sheep
  Homology: Cow: 100%; Dog: 77%; Goat: 100%; Guinea Pig: 77%; Horse: 77%; Human: 100%; Mouse: 83%; Pig: 93%; Rabbit: 75%; Rat: 83%; Sheep: 100%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 16kDa
• Gene Name: hemoglobin subunit gamma 2
• Database Link:
  NP_000175
  Entrez Gene 3048 Human
  UniProt ID P69892
• Background: The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.
• Synonyms: FLJ76540; Gamma-2-globin; methemoglobin; OTTHUMP00000069638