NALP12 (NLRP12) Rabbit Polyclonal Antibody

CAT#: TA358823

NLRP12 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: NLRP12 Sample Type: Hela Whole Cell lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human NLRP12
• Specificity: Expected reactivity: Cow, Dog, Human, Mouse, Pig, Rat
  Homology: Cow: 100%; Dog: 90%; Human: 100%; Mouse: 77%; Pig: 100%; Rat: 85%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 116kDa
• Gene Name: NLR family, pyrin domain containing 12
• Database Link:
  NP_653288
  Entrez Gene 91662 Human
  UniProt ID P59046
• Background: This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
• Synonyms: CLR19.3; FCAS2; Monarch-1; Monarch1; NALP12; PAN6; PYPAF7; RNO; RNO2