GGCT Rabbit Polyclonal Antibody

CAT#: TA358853

GGCT Antibody - C-terminal region

Product Images

WB Suggested Anti-GGCT Antibody Titration: 1.0 ug/ml Positive Control: Fetal Lung

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: Expected reactivity: Cow, Dog, Guinea Pig, Horse, Human, Rabbit, Rat
  Homology: Cow: 92%; Dog: 86%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Rabbit: 86%; Rat: 93%
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity Purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 21kDa
• Gene Name: gamma-glutamylcyclotransferase
• Database Link:
  NP_076956
  Entrez Gene 79017 Human
  UniProt ID O75223
• Background: The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Synonyms: C7orf24; CRF21; FLJ11717; gamma-glutamylcyclotransferase; GCTG; Ggc; MGC3077

Reference Data

• Protein Pathways: Glutathione metabolism