NALP1 (NLRP1) Rabbit Polyclonal Antibody

CAT#: TA359164

NLRP1 Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: NLRP1 Sample Tissue: Human 786-0 Whole Cell lysates Antibody Dilution: 2ug/ml

Specifications

Product Data

• Applications: WB
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human NLRP1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 162 kDa
• Gene Name: NLR family, pyrin domain containing 1
• Database Link:
  NP_001028225
  UniProt ID Q9C000
• Background: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined.
• Synonyms: CARD7; CLR17.1; DEFCAP; DEFCAP-L/S; DKFZp586O1822; KIAA0926; NAC; NALP1; PP1044; SLEV1; VAMAS1