IL5RA Rabbit Polyclonal Antibody

CAT#: TA359450

IL5RA Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: IL5RA Sample Tissue: Human Large Intestine Tumor lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IL5RA
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 36 kDa
• Gene Name: interleukin 5 receptor subunit alpha
• Database Link:
  NP_783855
  Entrez Gene 3568 Human
  UniProt ID Q01344-2
• Background: The protein encoded by this gene is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. This protein has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4. Several alternatively spliced transcript variants encoding four distinct isoforms have been reported.
• Synonyms: CD125; CDw125; HSIL5R3; IL-5R-alpha; IL5R; MGC26560; OTTHUMP00000115373; OTTHUMP00000206893; OTTHUMP00000206896