PMS1 Rabbit Polyclonal Antibody

CAT#: TA359481

PMS1 Antibody - middle region

Product Images

Host: Rabbit Target Name: PMS1 Sample Tissue: Human U937 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PMS1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 102 kDa
• Gene Name: PMS1 homolog 1, mismatch repair system component
• Database Link:
  NP_000525.1
  Entrez Gene 5378 Human
  UniProt ID P54277
• Background: This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome.
• Synonyms: DKFZp781M0253; FLJ98259; HNPCC3; hPMS1; PMSL1