VAC14 Rabbit Polyclonal Antibody

CAT#: TA359553

VAC14 Antibody - C-terminal region

Product Images

WB Suggested Anti-VAC14 antibody Titration: 1 ug/mL Sample Type: Human 293T Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human VAC14
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 86 kDa
• Gene Name: Vac14, PIKFYVE complex component
• Database Link:
  NP_060522.3
  Entrez Gene 55697 Human
  UniProt ID Q08AM6
• Background: The content of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2) in endosomal membranes changes dynamically with fission and fusion events that generate or absorb intracellular transport vesicles. VAC14 is a component of a trimolecular complex that tightly regulates the level of PtdIns(3,5)P2. Other components of this complex are the PtdIns(3,5)P2-synthesizing enzyme PIKFYVE (MIM 609414) and the PtdIns(3,5)P2 phosphatase FIG4 (MIM 609390). VAC14 functions as an activator of PIKFYVE.
• Synonyms: ArPIKfyve; FLJ10305; FLJ36622; FLJ46582; MGC149815; MGC149816; TAX1BP2; TRX