PDE8B Rabbit Polyclonal Antibody

CAT#: TA359702

PDE8B Antibody - middle region

Product Images

Host: Rabbit Target Name: PDE8B Sample Tissue: Human MDA-MB-435s lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PDE8B
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 64 kDa
• Gene Name: phosphodiesterase 8B
• Database Link:
  NP_001025022.1
  Entrez Gene 8622 Human
  UniProt ID B3KN77
• Background: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
• Synonyms: FLJ11212; HsPDE8B; PPNAD3