TFIP11 Rabbit Polyclonal Antibody

CAT#: TA359890

TFIP11 Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: TFP11 Sample Type: Fetal Liver lysates Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human TFP11
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 92kDa
• Gene Name: tuftelin interacting protein 11
• Database Link:
  NP_036275
  Entrez Gene 24144 Human
  UniProt ID Q9UBB9
• Background: This gene encodes a protein component of the spliceosome that promotes the release of the lariat-intron during late-stage splicing through the recruitment of a pre-mRNA splicing factor called DEAH-box helicase 15. The encoded protein contains a G-patch domain, a hallmark of RNA-processing proteins, that binds DEAH-box helicase 15. This protein contains an atypical nuclear localization sequence as well as a nuclear speckle-targeting sequence, enabling it to localize to distinct speckled regions within the cell nucleus. Polymorphisms in this gene are associated with dental caries suggesting a role in amelogenesis. Alternative splicing results in multiple transcript variants.
• Synonyms: bK445C9.6; DKFZP434B194; FLJ22086; hNtr1; NTR1; OTTHUMP00000198650; OTTHUMP00000198850; OTTHUMP00000198851; OTTHUMP00000198852; STIP; STIP-1; TIP39