Plastin L (LCP1) Rabbit Polyclonal Antibody

CAT#: TA360143

LCP1 Antibody - C-terminal region

Product Images

WB Suggested Anti-PLSL antibody Titration: 1 ug/mL Sample Type: Human Jurkat Whole Cell

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen for Anti-LCP1 antibody is: synthetic peptide directed towards the C-terminal region of Human PLSL
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 68 kDa
• Gene Name: lymphocyte cytosolic protein 1
• Database Link:
  XP_005266431.1
  Entrez Gene 3936 Human
  UniProt ID P13796
• Background: Plastins are a family of actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. In humans, two ubiquitous plastin isoforms (L and T) have been identified. Plastin 1 (otherwise known as Fimbrin) is a third distinct plastin isoform which is specifically expressed at high levels in the small intestine. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, melanocytes, etc.). However, L-plastin has been found in many types of malignant human cells of non-hemopoietic origin suggesting that its expression is induced accompanying tumorigenesis in solid tissues.
• Synonyms: CP64; DKFZp781A23186; FLJ25423; FLJ26114; FLJ39956; L-PLASTIN; LC64P; LCP-1; LPL; OTTHUMP00000018362; PLS2