p57 Kip2 (CDKN1C) Rabbit Polyclonal Antibody

CAT#: TA360532

CDKN1C Antibody - middle region

Product Images

Host: Rabbit Target Name: CDKN1C Sample Tissue: Human MCF7 Whole Cell Antibody Dilution: 1.0ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CDKN1C
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 32 kDa
• Gene Name: cyclin-dependent kinase inhibitor 1C
• Database Link:
  NP_000067.1
  Entrez Gene 1028 Human
  UniProt ID P49918
• Background: This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.
• Synonyms: BWCR; BWS; KIP2; p57; p57KIP2; WBS