CARD11 Rabbit Polyclonal Antibody

CAT#: TA360555

CARD11 Antibody - middle region

Product Images

Host: Rabbit Target Name: CARD11 Sample Tissue: Human HeLa Whole Cell lysates Antibody Dilution: 1ug/ml

• 

  Host: Mouse Target Name: CARD11 Sample Tissue: Mouse Brain Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CARD11
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 128 kDa
• Gene Name: caspase recruitment domain family member 11
• Database Link:
  NP_115791.3
  Entrez Gene 84433 Human
  UniProt ID Q8TES3
• Background: The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
• Synonyms: BIMP3; CARMA1; MGC133069