MRCL3 (MYL12A) Rabbit Polyclonal Antibody

CAT#: TA360739

MYL12A Antibody - N-terminal region

Product Images

Host: Rabbit Target Name: MYL12A Sample Tissue: Human THP-1 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MYL12A
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 18 kDa
• Gene Name: myosin light chain 12A
• Database Link:
  NP_001289976.1
  Entrez Gene 10627 Human
  UniProt ID P19105
• Background: This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
• Synonyms: MLC-2B; MLCB; MRCL3; MRLC3; MYL2B; RLC