Aromatase (CYP19A1) Rabbit Polyclonal Antibody

CAT#: TA360784

CYP19A1 Antibody - middle region

Product Images

Host: Rabbit Target Name: CYP19A1 Sample Tissue: Human MCF7 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CYP19A1
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 55 kDa
• Gene Name: cytochrome P450 family 19 subfamily A member 1
• Database Link:
  NP_000094.2
  Entrez Gene 1588 Human
  UniProt ID P11511
• Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative splicing results in multiple transcript variants.
• Synonyms: ARO; ARO1; Aromatase; CPV1; CYAR; CYP19; CYPXIX; MGC104309; OTTHUMP00000162543; P-450AROM