Endothelin B Receptor (EDNRB) Rabbit Polyclonal Antibody

CAT#: TA360923

EDNRB Antibody - C-terminal region

Product Images

Host: Rabbit Target Name: EDNRB Sample Tissue: Human HepG2 Whole Cell lysates Antibody Dilution: 1ug/ml

Specifications

Product Data

• Applications: WB
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human EDNRB
• Specificity: Expected reactivity: Human
• Formulation: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
• Concentration: lot specific
• Purification: Affinity purified
• Conjugation: Unconjugated
• Storage: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
• Predicted Protein Size: 49 kDa
• Gene Name: endothelin receptor type B
• Database Link:
  NP_000106.1
  Entrez Gene 1910 Human
  UniProt ID P24530
• Background: The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Synonyms: ABCDS; ET-B; ETB; ETBR; ETRB; HSCR; HSCR2